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The results obtained indicate that GLP-1RAs can have neuroprotective effects, mild vasoprotective and anti-inflammatory effects, delaying the increase in intraocular pressure and preventing reactive remodeling of astrocytes and blood vessels in glaucoma

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While moderate amounts can support gut and immune function, too much can thin this barrier, leading to increased intestinal permeability (leaky gut), inflammation and immune dysregulation An overgrowth of Akkermansia is linked to Multiple sclerosis, Parkinsons disease, Colorectal cancer, and Autoimmune flares So while the idea of taking a probiotic to boost GLP-1, and therefore reduce appetite or support blood sugar, sounds promising, forcing the gut ecosystem out of balance can backfire

10.1002/adfm.202100355 40 LinL.-S.SongJ.SongL.KeK.LiuY.ZhouZ.et al (2018)